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Stereoselective α-Tertiary Alkylation of N-(Arylacetyl)oxazolidinones

A method has been developed for the α-tertiary alkylation of zirconium enolates of N-(arylacetyl)oxazolidinones. This reaction directly installs an all-carbon quaternary center vicinal to a benzylic tertiary carbon in a highly diastereoselective manner.

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Detalhes bibliográficos
Publicado no:Synlett
Main Authors: Shim, Eunjae, Zakarian, Armen
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7544157/
https://ncbi.nlm.nih.gov/pubmed/33041522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0039-1690793
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