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Inhibition of overexpressed Kv3.4 augments HPV in endotoxemic mice

BACKGROUND: Hypoxic pulmonary vasoconstriction (HPV) is a reaction of the pulmonary vasculature upon hypoxia, diverting blood flow into ventilated areas to preserve oxygenation. It is impaired in endotoxemia or ARDS. Voltage gated potassium channels have been shown to play a key role in the regulati...

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Detalhes bibliográficos
Publicado no:BMC Pulm Med
Main Authors: Turzo, Maurizio, Metzger, Karin, Lasitschka, Felix, Weigand, Markus A., Busch, Cornelius J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7543677/
https://ncbi.nlm.nih.gov/pubmed/33032555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12890-020-01278-5
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