Nonmuscle myosin 2 regulates cortical stability during sprouting angiogenesis

Among the three nonmuscle myosin 2 (NM2) paralogs, NM 2A and 2B, but not 2C, are detected in endothelial cells. To study the role of NM2 in vascular formation, we ablate NM2 in endothelial cells in mice. Ablating NM2A, but not NM2B, results in reduced blood vessel coverage and increased vascular bra...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Biol Cell
Prif Awduron: Ma, Xuefei, Uchida, Yutaka, Wei, Tingyi, Liu, Chengyu, Adams, Ralf H., Kubota, Yoshiaki, Gutkind, J. Silvio, Mukouyama, Yoh-suke, Adelstein, Robert S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Cell Biology 2020
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7543065/
https://ncbi.nlm.nih.gov/pubmed/32583739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E20-03-0175
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