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Effects of U1 Small Nuclear Ribonucleoprotein Inhibition on the Expression of Genes Involved in Alzheimer’s Disease

[Image: see text] Deposition and dysfunction of U1 small nuclear ribonucleoprotein (snRNP) have been revealed in Alzheimer’s disease (AD), but whether U1 is involved in the amyloid precursor protein (APP) and Tau pathways remains unclear. Here, we investigate this by inhibiting the U1 components in...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Zhu, Wenbo, Wei, Xuefei, Wang, Yanyang, Li, Jingjing, Peng, Lu, Zhang, Kui, Bai, Bing
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7542834/
https://ncbi.nlm.nih.gov/pubmed/33043209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c03568
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