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A spontaneous mutation in DNA polymerase POL3 during in vitro passaging causes a hypermutator phenotype in Cryptococcus species
Passaging of microbes in vitro can lead to the selection of microevolved derivatives with differing properties to their original parent strains. One well characterised instance is the phenotypic differences observed between the series of strains derived from the type strain of the human pathogenic f...
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| Published in: | DNA Repair (Amst) |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7542539/ https://ncbi.nlm.nih.gov/pubmed/31838381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2019.102751 |
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