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Cryo-EM structure of the deltaretroviral intasome in complex with the PP2A regulatory subunit B56γ
Human T-cell lymphotropic virus type 1 (HTLV-1) is a deltaretrovirus and the most oncogenic pathogen. Many of the ~20 million HTLV-1 infected people will develop severe leukaemia or an ALS-like motor disease, unless a therapy becomes available. A key step in the establishment of infection is the int...
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| Veröffentlicht in: | Nat Commun |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7542444/ https://ncbi.nlm.nih.gov/pubmed/33028863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18874-y |
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