Cryo-EM structure of the deltaretroviral intasome in complex with the PP2A regulatory subunit B56γ

Human T-cell lymphotropic virus type 1 (HTLV-1) is a deltaretrovirus and the most oncogenic pathogen. Many of the ~20 million HTLV-1 infected people will develop severe leukaemia or an ALS-like motor disease, unless a therapy becomes available. A key step in the establishment of infection is the int...

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Vydáno v:Nat Commun
Hlavní autoři: Barski, Michał S., Minnell, Jordan J., Hodakova, Zuzana, Pye, Valerie E., Nans, Andrea, Cherepanov, Peter, Maertens, Goedele N.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7542444/
https://ncbi.nlm.nih.gov/pubmed/33028863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18874-y
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