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TIMP-2 regulates proliferation, invasion and STAT3-mediated cancer stem cell-dependent chemoresistance in ovarian cancer cells

BACKGROUND: The metzincin family of metalloproteinases and the tissue inhibitors of metalloproteinases (TIMPs) are essential proteins required for biological processes during cancer progression. This study aimed to determine the role of TIMP-2 in ovarian cancer progression and chemoresistance by red...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Escalona, Ruth M., Bilandzic, Maree, Western, Patrick, Kadife, Elif, Kannourakis, George, Findlay, Jock K., Ahmed, Nuzhat
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7542139/
https://ncbi.nlm.nih.gov/pubmed/33023532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07274-6
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