Towards the Clinical Development and Validation of a Thy1-Targeted Ultrasound Contrast Agent for the Early Detection of Pancreatic Ductal Adenocarcinoma

OBJECTIVES: Early detection of Pancreatic Ductal Adenocarcinoma (PDAC) represents the most significant step towards the treatment of this aggressive lethal disease. Previously, we engineered a pre-clinical Thy1-targeted microbubble (MB(Thy1)) contrast agent that specifically recognizes Thy1 antigen...

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Veröffentlicht in:Invest Radiol
Hauptverfasser: Bam, Rakesh, Daryaei, Iman, Abou-Elkacem, Lotfi, Vilches-Moure, Jose G., Meuillet, Emmanuelle J., Lutz, Amelie, Marinelli, Edmund R., Unger, Evan C., Gambhir, Sanjiv S., Paulmurugan, Ramasamy
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541735/
https://ncbi.nlm.nih.gov/pubmed/32569010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/RLI.0000000000000697
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