Ketamine as adjunct to midazolam treatment following soman-induced status epilepticus reduces seizure severity, epileptogenesis and brain pathology in plasma carboxylesterase knockout mice

Delayed treatment of cholinergic seizure results in benzodiazepine-refractory status epilepticus that is thought, at least in part, to result from maladaptive trafficking of N-methyl-D-aspartate (NMDA) and gamma aminobutyric acid type A (GABA(A)) receptors, the effects of which may be ameliorated by...

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Veröffentlicht in:Epilepsy Behav
Hauptverfasser: Marrero-Rosado, Brenda M., de Araujo Furtado, Marcio, Kundrick, Erica R., Walker, Katie A., Stone, Michael F., Schultz, Caroline R., Nguyen, Donna A., Lumley, Lucille A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541728/
https://ncbi.nlm.nih.gov/pubmed/32575012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yebeh.2020.107229
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