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Soman‐induced status epilepticus, epileptogenesis, and neuropathology in carboxylesterase knockout mice treated with midazolam

OBJECTIVE: Exposure to chemical warfare nerve agents (CWNAs), such as soman (GD), can induce status epilepticus (SE) that becomes refractory to benzodiazepines when treatment is delayed, leading to increased risk of epileptogenesis, severe neuropathology, and long‐term behavioral and cognitive defic...

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Détails bibliographiques
Publié dans:Epilepsia
Auteurs principaux: Marrero‐Rosado, Brenda, de Araujo Furtado, Marcio, Schultz, Caroline R., Stone, Michael, Kundrick, Erica, Walker, Katie, O’Brien, Sean, Du, Fu, Lumley, Lucille A.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6334636/
https://ncbi.nlm.nih.gov/pubmed/30368799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.14582
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