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Itch attenuates CD4 T-cell proliferation in mice by limiting WBP2 protein stability
To mount an antipathogen response, CD4 T cells must undergo rapid cell proliferation; however, poorly controlled expansion can result in diseases such as autoimmunity. One important regulator of T-cell activity is the E3 ubiquitin ligase Itch. Itch deficient patients suffer from extensive autoinflam...
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| Vydáno v: | Eur J Immunol |
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| Hlavní autoři: | , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7541725/ https://ncbi.nlm.nih.gov/pubmed/32459862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201948323 |
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