The Zika Virus Capsid Disrupts Corticogenesis by Suppressing Dicer Activity and miRNA Biogenesis

Zika virus (ZIKV) causes microcephaly and disrupts neurogenesis. Dicer-mediated miRNA biogenesis is required for embryonic brain development and has been suggested to be disrupted upon ZIKV infection. Here we mapped the ZIKV-host interactome in neural stem cells (NSCs) and found that Dicer is specif...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Stem Cell
Prif Awduron: Zeng, Jianxiong, Dong, Shupeng, Luo, Zhifei, Xie, Xiaochun, Fu, Bishi, Li, Ping, Liu, Chengrong, Yang, Xing, Chen, Yujie, Wang, Xin, Liu, Zhenshan, Wu, Jing, Yan, Youzhen, Wang, Feng, Chen, Jian-Fu, Zhang, Jian, Long, Gang, Goldman, Steven A., Li, Shitao, Zhao, Zhen, Liang, Qiming
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541724/
https://ncbi.nlm.nih.gov/pubmed/32763144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2020.07.012
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