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Aromatic carbohydrate amphiphile disrupts cancer spheroids and prevents relapse

Spheroids recapitulate the organization, heterogeneity and microenvironment of solid tumors. Herein, we targeted spatiotemporally the accelerated metabolism of proliferative cells located on the spheroid surface that ensure structure maintenance and/or growth. We demonstrate that phosphorylated carb...

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Publicat a:Nanoscale
Autors principals: Brito, Alexandra, Pereira, Patrícia M. R., Reis, Rui L., Ulijn, Rein V., Lewis, Jason S., Pires, Ricardo A., Pashkuleva, Iva
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541621/
https://ncbi.nlm.nih.gov/pubmed/32955076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0nr05008c
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