ATP modulates SLC7A5 (LAT1) synergistically with cholesterol

The plasma membrane transporter hLAT1 is responsible for providing cells with essential amino acids. hLAT1 is over-expressed in virtually all human cancers making the protein a hot-spot in the fields of cancer and pharmacology research. However, regulatory aspects of hLAT1 biology are still poorly u...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Cosco, Jessica, Scalise, Mariafrancesca, Colas, Claire, Galluccio, Michele, Martini, Riccardo, Rovella, Filomena, Mazza, Tiziano, Ecker, Gerhard F., Indiveri, Cesare
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541457/
https://ncbi.nlm.nih.gov/pubmed/33028978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73757-y
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