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Structure-guided covalent stabilization of coronavirus spike glycoprotein trimers in the closed conformation
SARS-CoV-2 is the causative agent of the COVID-19 pandemic, with 10 million infections and more than 500,000 fatalities by June 2020. To initiate infection, the SARS-CoV-2 spike (S) glycoprotein promotes attachment to the host cell surface and fusion of the viral and host membranes. Prefusion SARS-C...
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| Publicado en: | Nat Struct Mol Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group US
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7541350/ https://ncbi.nlm.nih.gov/pubmed/32753755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-020-0483-8 |
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