NF-κB and pSTAT3 synergistically drive G6PD overexpression and facilitate sensitivity to G6PD inhibition in ccRCC

BACKGROUND: Glucose 6-phosphate dehydrogenase (G6PD) serves key roles in cancer cell metabolic reprogramming, and has been reported to be involved in certain carcinogenesis. Previous results from our laboratory demonstrated that overexpressed G6PD was a potential prognostic biomarker in clear cell r...

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Dades bibliogràfiques
Publicat a:Cancer Cell Int
Autors principals: Zhang, Qiao, Yang, Zhe, Ni, Yueli, Bai, Honggang, Han, Qiaoqiao, Yi, Zihan, Yi, Xiaojia, Agbana, Yannick Luther, Kuang, Yingmin, Zhu, Yuechun
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Primary Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541270/
https://ncbi.nlm.nih.gov/pubmed/33041664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-01576-2
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