NF-κB and pSTAT3 synergistically drive G6PD overexpression and facilitate sensitivity to G6PD inhibition in ccRCC

BACKGROUND: Glucose 6-phosphate dehydrogenase (G6PD) serves key roles in cancer cell metabolic reprogramming, and has been reported to be involved in certain carcinogenesis. Previous results from our laboratory demonstrated that overexpressed G6PD was a potential prognostic biomarker in clear cell r...

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Detalhes bibliográficos
Publicado no:Cancer Cell Int
Main Authors: Zhang, Qiao, Yang, Zhe, Ni, Yueli, Bai, Honggang, Han, Qiaoqiao, Yi, Zihan, Yi, Xiaojia, Agbana, Yannick Luther, Kuang, Yingmin, Zhu, Yuechun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Primary Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541270/
https://ncbi.nlm.nih.gov/pubmed/33041664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-01576-2
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