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Oxysophocarpine suppresses hepatocellular carcinoma growth and sensitizes the therapeutic blockade of anti‐Lag‐3 via reducing FGL1 expression

Hepatocellular carcinoma (HCC) is an aggressive malignancy with limited effective treatments and ranks as the second most lethal tumor. Immunotherapy has brought great hope for HCC treatment. Oxysophocarpine is a bioactive alkaloid which poses various pharmacological functions including neuroprotect...

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Vydáno v:Cancer Med
Hlavní autoři: Wang, Jianchu, Wei, Wang, Tang, Qianli, Lu, Libai, Luo, Zongjiang, Li, Wenchuan, Lu, Yuan, Pu, Jian
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541159/
https://ncbi.nlm.nih.gov/pubmed/32810392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.3151
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