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Oxysophocarpine suppresses hepatocellular carcinoma growth and sensitizes the therapeutic blockade of anti‐Lag‐3 via reducing FGL1 expression

Hepatocellular carcinoma (HCC) is an aggressive malignancy with limited effective treatments and ranks as the second most lethal tumor. Immunotherapy has brought great hope for HCC treatment. Oxysophocarpine is a bioactive alkaloid which poses various pharmacological functions including neuroprotect...

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Bibliografske podrobnosti
izdano v:Cancer Med
Main Authors: Wang, Jianchu, Wei, Wang, Tang, Qianli, Lu, Libai, Luo, Zongjiang, Li, Wenchuan, Lu, Yuan, Pu, Jian
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541159/
https://ncbi.nlm.nih.gov/pubmed/32810392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.3151
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