Aromatic (19)F–(13)C TROSY—[(19)F, (13)C]‐Pyrimidine Labeling for NMR Spectroscopy of RNA

We present the access to [5‐(19)F, 5‐(13)C]‐uridine and ‐cytidine phosphoramidites for the production of site‐specifically modified RNAs up to 65 nucleotides (nts). The amidites were used to introduce [5‐(19)F, 5‐(13)C]‐pyrimidine labels into five RNAs—the 30 nt human immunodeficiency virus trans ac...

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Bibliografiska uppgifter
I publikationen:Angew Chem Int Ed Engl
Huvudupphovsmän: Nußbaumer, Felix, Plangger, Raphael, Roeck, Manuel, Kreutz, Christoph
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2020
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7540360/
https://ncbi.nlm.nih.gov/pubmed/32558232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202006577
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