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Inhibition of MyD88 by a novel inhibitor reverses two-thirds of the infarct area in myocardial ischemia and reperfusion injury

Cardiomyocytes, macrophages, and fibroblasts play important roles in inflammation and repair during myocardial ischemia/reperfusion injury (MIRI). Myeloid differentiation primary response 88 (MyD88) is upregulated in immunocytes, cardiomyocytes, and fibroblasts during MIRI. MyD88 induces the secreti...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Miao, Yan, Ding, Zuochuan, Zou, Zhimiao, Yang, Yang, Yang, Min, Zhang, Xiaoqian, Li, Zeyang, Zhou, Liang, Zhang, Limin, Zhang, Xue, Du, Dunfeng, Jiang, Fengchao, Zhou, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7540094/
https://ncbi.nlm.nih.gov/pubmed/33042411
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