Pharmacological inhibition of MyD88 homodimerization counteracts renal ischemia reperfusion-induced progressive renal injury in vivo and in vitro

The activation of innate immunity via myeloid differentiation factor 88 (MyD88) contributes to ischemia reperfusion (I/R) induced acute kidney injury (AKI) and chronic kidney injury. However, since there have not yet been any effective therapy, the exact pharmacological role of MyD88 in the preventi...

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Publicado no:Sci Rep
Main Authors: Zhang, Li-Min, Liu, Jian-Hua, Xue, Cheng-Biao, Li, Ming-Qiang, Xing, Shuai, Zhang, Xue, He, Wen-Tao, Jiang, Feng-Chao, Lu, Xia, Zhou, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887891/
https://ncbi.nlm.nih.gov/pubmed/27246399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26954
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