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Roles of glycogen synthase kinase 3 alpha and calcineurin in regulating the ability of sperm to fertilize eggs

Glycogen synthase kinase 3 (GSK3) was identified as an enzyme regulating sperm protein phosphatase. The GSK3α paralog, but not GSK3β, is essential for sperm function. Sperm lacking GSK3α display altered motility and are unable to undergo hyperactivation, which is essential for fertilization. Male mi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:FASEB J
Egile Nagusiak: Dey, Souvik, Eisa, Alaa, Kline, Douglas, Wagner, Florence F., Abeysirigunawardena, Sanjaya, Vijayaraghavan, Srinivasan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7539848/
https://ncbi.nlm.nih.gov/pubmed/31914663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201902163R
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