Llwytho...

Roles of glycogen synthase kinase 3 alpha and calcineurin in regulating the ability of sperm to fertilize eggs

Glycogen synthase kinase 3 (GSK3) was identified as an enzyme regulating sperm protein phosphatase. The GSK3α paralog, but not GSK3β, is essential for sperm function. Sperm lacking GSK3α display altered motility and are unable to undergo hyperactivation, which is essential for fertilization. Male mi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:FASEB J
Prif Awduron: Dey, Souvik, Eisa, Alaa, Kline, Douglas, Wagner, Florence F., Abeysirigunawardena, Sanjaya, Vijayaraghavan, Srinivasan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7539848/
https://ncbi.nlm.nih.gov/pubmed/31914663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201902163R
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