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Acetylation of Werner protein at K1127 and K1117 is important for nuclear trafficking and DNA repair
Werner syndrome is a rare autosomal recessive disorder where Werner (WRN) gene is mutated. Being a nucleolar protein, during DNA damage, WRN translocates at the damage site where its catalytic function is required in DNA repair. Several studies have indicated that WRN acetylation may modulate WRN tr...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | DNA Repair (Amst) |
|---|---|
| Prif Awduron: | , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2019
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7539646/ https://ncbi.nlm.nih.gov/pubmed/31085421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2019.04.010 |
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