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Deep Intact Proteoform Characterization in Human Cell Lysate using High-pH and Low-pH Reversed-Phase Liquid Chromatography
Post-translational modifications (PTMs) play critical roles in biological processes and have significant effects on the structures and dynamics of proteins. Top-down proteomics methods were developed for and applied to the study of intact proteins and their PTMs in human samples. However, the large...
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| Vydáno v: | J Am Soc Mass Spectrom |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7539543/ https://ncbi.nlm.nih.gov/pubmed/31755044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-019-02315-2 |
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