Therapeutic potential of a novel prodrug of green tea extract in induction of apoptosis via ERK/JNK and Akt signaling pathway in human endometrial cancer

BACKGROUND: Previous studies have shown a major green tea polyphenol (−)-epigallocatechin-3-gallate ((−)-EGCG) as a powerful anti-cancer agent. However, its poor bioavailability and requirement of a high dosage to manifest activity have restricted its clinical application. Recently, our team synthes...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Man, Gene Chi Wai, Wang, Jianzhang, Song, Yi, Wong, Jack Ho, Zhao, Yu, Lau, Tat San, Leung, Kam Tong, Chan, Tak Hang, Wang, Huating, Kwong, Joseph, Ng, Tzi Bun, Wang, Chi Chiu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7539473/
https://ncbi.nlm.nih.gov/pubmed/33023525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07455-3
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