Therapeutic potential of a novel prodrug of green tea extract in induction of apoptosis via ERK/JNK and Akt signaling pathway in human endometrial cancer

BACKGROUND: Previous studies have shown a major green tea polyphenol (−)-epigallocatechin-3-gallate ((−)-EGCG) as a powerful anti-cancer agent. However, its poor bioavailability and requirement of a high dosage to manifest activity have restricted its clinical application. Recently, our team synthes...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:BMC Cancer
Päätekijät: Man, Gene Chi Wai, Wang, Jianzhang, Song, Yi, Wong, Jack Ho, Zhao, Yu, Lau, Tat San, Leung, Kam Tong, Chan, Tak Hang, Wang, Huating, Kwong, Joseph, Ng, Tzi Bun, Wang, Chi Chiu
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2020
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7539473/
https://ncbi.nlm.nih.gov/pubmed/33023525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07455-3
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