Frequency of the TP53 R337H variant in sporadic breast cancer and its impact on genomic instability

The R337H is a TP53 germline pathogenic variant that has been associated with several types of cancers, including breast cancer. Our main objective was to determine the frequency of the R337H variant in sporadic breast cancer patients from Paraná state, South Brazil, its association with prognosis a...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Mathias, Carolina, Bortoletto, Stéfanne, Centa, Ariana, Komechen, Heloisa, Lima, Rubens S., Fonseca, Aline S., Sebastião, Ana Paula, Urban, Cícero A., Soares, Emerson W. S., Prando, Carolina, Figueiredo, Bonald C., Cavalli, Iglenir J., Cavalli, Luciane R., Ribeiro, Enilze M. F. S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7539008/
https://ncbi.nlm.nih.gov/pubmed/33024147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73282-y
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