IL-12 DNA Displays Efficient Adjuvant Effects Improving Immunogenicity of Ag85A in DNA Prime/MVA Boost Immunizations

Mycobacterium tuberculosis (Mtb) infection is one of the leading causes of death worldwide. The Modified Vaccinia Ankara (MVA) vaccine vector expressing the mycobacterial antigen 85A (MVA85A) was demonstrated to be safe, although it did not improve BCG efficacy, denoting the need to search for impro...

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Detalles Bibliográficos
Publicado en:Front Cell Infect Microbiol
Main Authors: Morelli, María Paula, Del Medico Zajac, María Paula, Pellegrini, Joaquín Miguel, Amiano, Nicolás Oscar, Tateosian, Nancy Liliana, Calamante, Gabriela, Gherardi, María Magdalena, García, Verónica Edith
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
Assuntos:
Cellular and Infection Microbiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7538621/
https://ncbi.nlm.nih.gov/pubmed/33072631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2020.581812
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