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Sofosbuvir terminated RNA is more resistant to SARS-CoV-2 proofreader than RNA terminated by Remdesivir

SARS-CoV-2 is responsible for COVID-19, resulting in the largest pandemic in over a hundred years. After examining the molecular structures and activities of hepatitis C viral inhibitors and comparing hepatitis C virus and coronavirus replication, we previously postulated that the FDA-approved hepat...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Jockusch, Steffen, Tao, Chuanjuan, Li, Xiaoxu, Chien, Minchen, Kumar, Shiv, Morozova, Irina, Kalachikov, Sergey, Russo, James J., Ju, Jingyue
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7538426/
https://ncbi.nlm.nih.gov/pubmed/33024223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73641-9
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