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Proinflammatory cytokines and ARDS pulmonary edema fluid induce CD40 on human mesenchymal stromal cells—A potential mechanism for immune modulation

Human mesenchymal stem/stromal cells (hMSCs) are a promising therapy for acute respiratory distress syndrome (ARDS) and other inflammatory conditions. While considerable research has focused on paracrine effects and mitochondrial transfer that improve lung fluid balance, hMSCs are well known to have...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Wilfong, Erin M., Croze, Roxanne, Fang, Xiaohui, Schwede, Matthew, Niemi, Erene, López, Giselle Y., Lee, Jae-Woo, Nakamura, Mary C., Matthay, Michael A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7537876/
https://ncbi.nlm.nih.gov/pubmed/33021986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0240319
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