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Proinflammatory cytokines and ARDS pulmonary edema fluid induce CD40 on human mesenchymal stromal cells—A potential mechanism for immune modulation

Human mesenchymal stem/stromal cells (hMSCs) are a promising therapy for acute respiratory distress syndrome (ARDS) and other inflammatory conditions. While considerable research has focused on paracrine effects and mitochondrial transfer that improve lung fluid balance, hMSCs are well known to have...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wilfong, Erin M., Croze, Roxanne, Fang, Xiaohui, Schwede, Matthew, Niemi, Erene, López, Giselle Y., Lee, Jae-Woo, Nakamura, Mary C., Matthay, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7537876/
https://ncbi.nlm.nih.gov/pubmed/33021986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0240319
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