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KRAS, NRAS, and BRAF mutations in plasma cell myeloma at a single Korean institute

BACKGROUND: Plasma cell myeloma (PCM) is a genetically heterogeneous disease. The genetic spectrum of PCM has been expanded to mutations such as KRAS, NRAS, and BRAF genes in the RAS-RAF-MAPK pathway. In this study, we have evaluated the frequency of these mutations and their significance, including...

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Detalhes bibliográficos
Publicado no:Blood Res
Main Authors: Kim, Yonggoo, Park, Sung-Soo, Min, Chang-Ki, Lee, Gun Dong, Son, Jungok, Jo, Sung Jin, Han, Eunhee, Han, Kyungja, Kim, Myungshin
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society of Hematology; Korean Society of Blood and Marrow Transplantation; Korean Society of Pediatric Hematology-Oncology; Korean Society on Thrombosis and Hemostasis 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7536562/
https://ncbi.nlm.nih.gov/pubmed/32989177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5045/br.2020.2020137
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