KRAS/NRAS/BRAF Mutations as Potential Targets in Multiple Myeloma

In multiple myeloma the mutational profile is mainly represented by translocations involving chromosome 14 and by single nucleotide mutations, frequently involving genes implicated in the mitogen activated protein kinase (MAPK) pathway, as KRAS, NRAS, and, less frequently, BRAF. Because KRAS/NRAS/BR...

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Detalles Bibliográficos
Publicado en:Front Oncol
Main Authors: Pasca, Sergiu, Tomuleasa, Ciprian, Teodorescu, Patric, Ghiaur, Gabriel, Dima, Delia, Moisoiu, Vlad, Berce, Cristian, Stefan, Cristina, Ciechanover, Aaron, Einsele, Herman
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
Assuntos:
Oncology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6821642/
https://ncbi.nlm.nih.gov/pubmed/31709194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01137
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