KRAS/NRAS/BRAF Mutations as Potential Targets in Multiple Myeloma

In multiple myeloma the mutational profile is mainly represented by translocations involving chromosome 14 and by single nucleotide mutations, frequently involving genes implicated in the mitogen activated protein kinase (MAPK) pathway, as KRAS, NRAS, and, less frequently, BRAF. Because KRAS/NRAS/BR...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Pasca, Sergiu, Tomuleasa, Ciprian, Teodorescu, Patric, Ghiaur, Gabriel, Dima, Delia, Moisoiu, Vlad, Berce, Cristian, Stefan, Cristina, Ciechanover, Aaron, Einsele, Herman
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6821642/
https://ncbi.nlm.nih.gov/pubmed/31709194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01137
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