KRAS/NRAS/BRAF Mutations as Potential Targets in Multiple Myeloma

In multiple myeloma the mutational profile is mainly represented by translocations involving chromosome 14 and by single nucleotide mutations, frequently involving genes implicated in the mitogen activated protein kinase (MAPK) pathway, as KRAS, NRAS, and, less frequently, BRAF. Because KRAS/NRAS/BR...

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發表在:Front Oncol
Main Authors: Pasca, Sergiu, Tomuleasa, Ciprian, Teodorescu, Patric, Ghiaur, Gabriel, Dima, Delia, Moisoiu, Vlad, Berce, Cristian, Stefan, Cristina, Ciechanover, Aaron, Einsele, Herman
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2019
主題:
Oncology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6821642/
https://ncbi.nlm.nih.gov/pubmed/31709194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01137
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