KRAS/NRAS/BRAF Mutations as Potential Targets in Multiple Myeloma

In multiple myeloma the mutational profile is mainly represented by translocations involving chromosome 14 and by single nucleotide mutations, frequently involving genes implicated in the mitogen activated protein kinase (MAPK) pathway, as KRAS, NRAS, and, less frequently, BRAF. Because KRAS/NRAS/BR...

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Bibliografische gegevens
Gepubliceerd in:Front Oncol
Hoofdauteurs: Pasca, Sergiu, Tomuleasa, Ciprian, Teodorescu, Patric, Ghiaur, Gabriel, Dima, Delia, Moisoiu, Vlad, Berce, Cristian, Stefan, Cristina, Ciechanover, Aaron, Einsele, Herman
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2019
Onderwerpen:
Oncology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6821642/
https://ncbi.nlm.nih.gov/pubmed/31709194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01137
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