Glioma-derived IL-33 orchestrates an inflammatory brain tumor microenvironment that accelerates glioma progression

Despite a deeper molecular understanding, human glioblastoma remains one of the most treatment refractory and fatal cancers. It is known that the presence of macrophages and microglia impact glioblastoma tumorigenesis and prevent durable response. Herein we identify the dual function cytokine IL-33...

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Vydáno v:Nat Commun
Hlavní autoři: De Boeck, Astrid, Ahn, Bo Young, D’Mello, Charlotte, Lun, Xueqing, Menon, Shyam V., Alshehri, Mana M., Szulzewsky, Frank, Shen, Yaoqing, Khan, Lubaba, Dang, Ngoc Ha, Reichardt, Elliott, Goring, Kimberly-Ann, King, Jennifer, Grisdale, Cameron J., Grinshtein, Natalie, Hambardzumyan, Dolores, Reilly, Karlyne M., Blough, Michael D., Cairncross, J. Gregory, Yong, V. Wee, Marra, Marco A., Jones, Steven J. M., Kaplan, David R., McCoy, Kathy D., Holland, Eric C., Bose, Pinaki, Chan, Jennifer A., Robbins, Stephen M., Senger, Donna L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7536425/
https://ncbi.nlm.nih.gov/pubmed/33020472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18569-4
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