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Novel 199 base pair NEFH promoter drives expression in retinal ganglion cells

Retinal ganglion cells (RGCs) are known to be involved in several ocular disorders, including glaucoma and Leber hereditary optic neuropathy (LHON), and hence represent target cells for gene therapies directed towards these diseases. Restricting gene therapeutics to the target cell type in many situ...

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Detalhes bibliográficos
Publicado no:Sci Rep
Principais autores: Millington-Ward, Sophia, Chadderton, Naomi, Berkeley, Megan, Finnegan, Laura K., Hanlon, Killian S., Carrigan, Matthew, Humphries, Peter, Kenna, Paul F., Palfi, Arpad, Farrar, G. Jane
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7536420/
https://ncbi.nlm.nih.gov/pubmed/33020509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73257-z
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