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Cdc6 disruption leads to centrosome abnormalities and chromosome instability in pancreatic cancer cells

Cell division cycle 6 (Cdc6) plays key roles in regulating DNA replication, and activation and maintenance of cell cycle check points. In addition, Cdc6 exerts oncogenic properties via genomic instability associated with incomplete DNA replication. This study aimed to examine the effects of Cdc6 on...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Youn, Yuna, Lee, Jong-chan, Kim, Jaihwan, Kim, Jae Hyeong, Hwang, Jin-Hyeok
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7536414/
https://ncbi.nlm.nih.gov/pubmed/33020506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73474-6
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