Molecular stratification of endometrioid ovarian carcinoma predicts clinical outcome

Endometrioid ovarian carcinoma (EnOC) demonstrates substantial clinical and molecular heterogeneity. Here, we report whole exome sequencing of 112 EnOC cases following rigorous pathological assessment. We detect a high frequency of mutation in CTNNB1 (43%), PIK3CA (43%), ARID1A (36%), PTEN (29%), KR...

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Bibliografiske detaljer
Udgivet i:	Nat Commun
Main Authors:	Hollis, Robert L., Thomson, John P., Stanley, Barbara, Churchman, Michael, Meynert, Alison M., Rye, Tzyvia, Bartos, Clare, Iida, Yasushi, Croy, Ian, Mackean, Melanie, Nussey, Fiona, Okamoto, Aikou, Semple, Colin A., Gourley, Charlie, Herrington, C. Simon
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group UK 2020
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC7536188/ https://ncbi.nlm.nih.gov/pubmed/33020491 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18819-5
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Molecular stratification of endometrioid ovarian carcinoma predicts clinical outcome

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