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Exploiting aneuploidy-imposed stresses and coping mechanisms to battle cancer
Aneuploidy, an irregular number of chromosomes in cells, is a hallmark feature of cancer. Aneuploidy results from chromosomal instability (CIN) and occurs in almost 90% of all tumours. While many cancers display an ongoing CIN phenotype, cells can also be aneuploid without displaying CIN. CIN drives...
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| Publicado no: | Open Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7536071/ https://ncbi.nlm.nih.gov/pubmed/32873156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.200148 |
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