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Multi-stability in cellular differentiation enabled by a network of three mutually repressing master regulators

Identifying the design principles of complex regulatory networks driving cellular decision-making remains essential to decode embryonic development as well as enhance cellular reprogramming. A well-studied network motif involved in cellular decision-making is a toggle switch—a set of two opposing tr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J R Soc Interface
Hauptverfasser: Duddu, Atchuta Srinivas, Sahoo, Sarthak, Hati, Souvadra, Jhunjhunwala, Siddharth, Jolly, Mohit Kumar
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Royal Society 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7536062/
https://ncbi.nlm.nih.gov/pubmed/32993428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2020.0631
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