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Hybrid E/M Phenotype(s) and Stemness: A Mechanistic Connection Embedded in Network Topology

Metastasis remains an unsolved clinical challenge. Two crucial features of metastasizing cancer cells are (a) their ability to dynamically move along the epithelial–hybrid–mesenchymal spectrum and (b) their tumor initiation potential or stemness. With increasing functional characterization of hybrid...

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Bibliographische Detailangaben
Veröffentlicht in:J Clin Med
Hauptverfasser: Pasani, Satwik, Sahoo, Sarthak, Jolly, Mohit Kumar
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7794989/
https://ncbi.nlm.nih.gov/pubmed/33375334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm10010060
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