M2 cortex-dorsolateral striatum stimulation reverses motor symptoms and synaptic deficits in Huntington’s disease

Huntington’s disease (HD) is a neurological disorder characterized by motor disturbances. HD pathology is most prominent in the striatum, the central hub of the basal ganglia. The cerebral cortex is the main striatal afferent, and progressive cortico-striatal disconnection characterizes HD. We mappe...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Fernández-García, Sara, Conde-Berriozabal, Sara, García-García, Esther, Gort-Paniello, Clara, Bernal-Casas, David, García-Díaz Barriga, Gerardo, López-Gil, Javier, Muñoz-Moreno, Emma, Soria, Guadalupe, Campa, Leticia, Artigas, Francesc, Rodríguez, Manuel José, Alberch, Jordi, Masana, Mercè
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7535932/
https://ncbi.nlm.nih.gov/pubmed/33016873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.57017
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