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Structure activity relationship of novel antiviral nucleosides against Enterovirus A71
Various (North)-methanocarba adenosine derivatives, containing rigid bicyclo[3.1.0]hexane ribose substitution, were screened for activity against representative viruses, and inhibition was observed after treatment of Enterovirus A71 with a 2-chloro-N(6)-1-cyclopropyl-2-methylpropan-1-yl derivative (...
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| Publicado no: | Bioorg Med Chem Lett |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier Science Ltd
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7534897/ https://ncbi.nlm.nih.gov/pubmed/33031923 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2020.127599 |
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