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Dynamic RMST curves for survival analysis in clinical trials

BACKGROUND: The data from immuno-oncology (IO) therapy trials often show delayed effects, cure rate, crossing hazards, or some mixture of these phenomena. Thus, the proportional hazards (PH) assumption is often violated such that the commonly used log-rank test can be very underpowered. In these tri...

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Detalhes bibliográficos
Publicado no:BMC Med Res Methodol
Main Authors: Liao, Jason J. Z., Liu, G. Frank, Wu, Wen-Chi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7534804/
https://ncbi.nlm.nih.gov/pubmed/32854619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12874-020-01098-5
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