Passive Transfer of Vaccine-Elicited Antibodies Protects Against SIV in Rhesus Macaques

Several HIV-1 and SIV vaccine candidates have been shown to provide partial protection against viral challenges in rhesus macaques. However, the protective efficacy of vaccine-elicited polyclonal antibodies has not previously been demonstrated in adoptive transfer studies in nonhuman primates. In th...

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Published in:Cell
Main Authors: Alter, Galit, Yu, Wen-Han, Chandrashekar, Abishek, Borducchi, Erica N., Ghneim, Khader, Sharma, Ashish, Nedellec, Rebecca, McKenney, Katherine R., Linde, Caitlyn, Broge, Thomas, Suscovich, Todd J., Linnekin, Tom, Abbink, Peter, Mercado, Noe B., Nkolola, Joseph P., McMahan, Katherine, Bondzie, Esther A., Hamza, Venous, Peter, Lauren, Kordana, Nicole, Mahrokhian, Shant, Seaman, Michael S., Li, Wenjun, Lewis, Mark G., Lauffenburger, Douglas A., Hangartner, Lars, Sekaly, Rafick-Pierre, Barouch, Dan H.
Format: Artigo
Language:Inglês
Published: 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7534693/
https://ncbi.nlm.nih.gov/pubmed/33007262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2020.08.033
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