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Temporal activation of LRH‐1 and RAR‐γ in human pluripotent stem cells induces a functional naïve‐like state

Naïve pluripotency can be established in human pluripotent stem cells (hPSCs) by manipulation of transcription factors, signaling pathways, or a combination thereof. However, differences exist in the molecular and functional properties of naïve hPSCs generated by different protocols, which include v...

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Détails bibliographiques
Publié dans:EMBO Rep
Auteurs principaux: Taei, Adeleh, Kiani, Tahereh, Taghizadeh, Zeinab, Moradi, Sharif, Samadian, Azam, Mollamohammadi, Sepideh, Sharifi‐Zarchi, Ali, Guenther, Stefan, Akhlaghpour, Azimeh, Asgari Abibeiglou, Behrouz, Najar‐Asl, Mostafa, Karamzadeh, Razieh, Khalooghi, Keynoosh, Braun, Thomas, Hassani, Seyedeh‐Nafiseh, Baharvand, Hossein
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7534641/
https://ncbi.nlm.nih.gov/pubmed/33252195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201847533
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