Inherent Immune Cell Variation Within Colonic Segments Presents Challenges for Clinical Trial Design

BACKGROUND AND AIMS: Intestinal biopsy sampling during IBD trials represents a valuable adjunct strategy for understanding drug responses at the tissue level. Given the length and distinctive embryonic origins of the proximal and distal colon, we investigated whether inherent regional differences of...

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Detalhes bibliográficos
Publicado no:J Crohns Colitis
Main Authors: Tyler, Christopher J, Guzman, Mauricio, Lundborg, Luke R, Yeasmin, Shaila, Perez-Jeldres, Tamara, Yarur, Andres, Behm, Brian, Dulai, Parambir S, Patel, Derek, Bamias, Giorgos, Rivera-Nieves, Jesús
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7533898/
https://ncbi.nlm.nih.gov/pubmed/32239151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ecco-jcc/jjaa067
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