Regulation of hepatic insulin signaling and glucose homeostasis by sphingosine kinase 2

Sphingolipid dysregulation is often associated with insulin resistance, while the enzymes controlling sphingolipid metabolism are emerging as therapeutic targets for improving insulin sensitivity. We report herein that sphingosine kinase 2 (SphK2), a key enzyme in sphingolipid catabolism, plays a cr...

詳細記述

保存先:
書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Aji, Gulibositan, Huang, Yu, Ng, Mei Li, Wang, Wei, Lan, Tian, Li, Min, Li, Yufei, Chen, Qi, Li, Rui, Yan, Sishan, Tran, Collin, Burchfield, James G., Couttas, Timothy A., Chen, Jinbiao, Chung, Long Hoa, Liu, Da, Wadham, Carol, Hogg, Philip J., Gao, Xin, Vadas, Mathew A., Gamble, Jennifer R., Don, Anthony S., Xia, Pu, Qi, Yanfei
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2020
主題:
Biological Sciences
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7533871/
https://ncbi.nlm.nih.gov/pubmed/32917816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2007856117
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